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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CDK13 All Species: 10.91
Human Site: S424 Identified Species: 26.67
UniProt: Q14004 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0.11
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q14004 NP_003709.3 1512 164923 S424 S R H S R S R S R H R L S R S
Chimpanzee Pan troglodytes XP_001139939 1512 164915 S424 S R H S R S R S R H R L S R S
Rhesus Macaque Macaca mulatta XP_001088594 1490 164086 D416 A A A A A K M D G K E S K G S
Dog Lupus familis XP_533082 1377 150158 H377 A G A S Q T N H V K D V K K L
Cat Felis silvestris
Mouse Mus musculus Q69ZA1 1511 164590 S425 S R H S R S R S R H R L S R S
Rat Rattus norvegicus Q3MJK5 1484 163772 S399 S S L G A E L S R K K K E R A
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_425866 1032 115177 G61 Q E T A A P L G A V I K P L V
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_687417 1286 141523 A315 P Y E Q G E F A G S P Y G Q R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P46551 730 82410
Sea Urchin Strong. purpuratus XP_789337 1264 139419 V290 Q K Y R K K T V Q A A K A K V
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.8 41.4 82.5 N.A. 95.1 41.6 N.A. N.A. 29.7 N.A. 44 N.A. N.A. N.A. 24.6 32.6
Protein Similarity: 100 99.8 53.5 84.5 N.A. 96.8 53.9 N.A. N.A. 37.9 N.A. 55 N.A. N.A. N.A. 33.3 46.9
P-Site Identity: 100 100 6.6 6.6 N.A. 100 26.6 N.A. N.A. 0 N.A. 0 N.A. N.A. N.A. 0 0
P-Site Similarity: 100 100 20 40 N.A. 100 40 N.A. N.A. 6.6 N.A. 13.3 N.A. N.A. N.A. 0 40
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 20 10 20 20 30 0 0 10 10 10 10 0 10 0 10 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 10 0 0 10 0 0 0 0 % D
% Glu: 0 10 10 0 0 20 0 0 0 0 10 0 10 0 0 % E
% Phe: 0 0 0 0 0 0 10 0 0 0 0 0 0 0 0 % F
% Gly: 0 10 0 10 10 0 0 10 20 0 0 0 10 10 0 % G
% His: 0 0 30 0 0 0 0 10 0 30 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 10 0 0 0 0 % I
% Lys: 0 10 0 0 10 20 0 0 0 30 10 30 20 20 0 % K
% Leu: 0 0 10 0 0 0 20 0 0 0 0 30 0 10 10 % L
% Met: 0 0 0 0 0 0 10 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 10 0 0 0 0 0 0 0 0 % N
% Pro: 10 0 0 0 0 10 0 0 0 0 10 0 10 0 0 % P
% Gln: 20 0 0 10 10 0 0 0 10 0 0 0 0 10 0 % Q
% Arg: 0 30 0 10 30 0 30 0 40 0 30 0 0 40 10 % R
% Ser: 40 10 0 40 0 30 0 40 0 10 0 10 30 0 40 % S
% Thr: 0 0 10 0 0 10 10 0 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 0 0 0 10 10 10 0 10 0 0 20 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 10 10 0 0 0 0 0 0 0 0 10 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _